Document Type

Article

Publication Date

10-13-2015

Publication Title

PNAS

Abstract

Reconstructing the phylogenetic relationships that unite all line- ages (the tree of life) is a grand challenge. The paucity of homologous character data across disparately related lineages currently renders direct phylogenetic inference untenable. To reconstruct a compre- hensive tree of life, we therefore synthesized published phylogenies, together with taxonomic classifications for taxa never incorporated into a phylogeny. We present a draft tree containing 2.3 million tips— the Open Tree of Life. Realization of this tree required the assembly of two additional community resources: (i) a comprehensive global reference taxonomy and (ii) a database of published phylogenetic trees mapped to this taxonomy. Our open source framework facili- tates community comment and contribution, enabling the tree to be continuously updated when new phylogenetic and taxonomic data become digitally available. Although data coverage and phylogenetic conflict across the Open Tree of Life illuminate gaps in both the un- derlying data available for phylogenetic reconstruction and the pub- lication of trees as digital objects, the tree provides a compelling starting point for community contribution. This comprehensive tree will fuel fundamental research on the nature of biological diversity, ultimately providing up-to-date phylogenies for downstream applica- tions in comparative biology, ecology, conservation biology, climate change, agriculture, and genomics.

Keywords

phylogeny, taxonomy, tree of life, biodiversity, synthesis

Volume

112

Issue

41

First Page

12764

Last Page

12769

DOI

doi/10.1073/pnas.1423041112

Rights

Copyright (2015) National Academy of Sciences

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Biology Commons

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