PLOS Neglected Tropical Diseases
Filarial nematodes cause serious and debilitating infections in human populations of tropical countries, contributing to an entrenched cycle of poverty. Only one human filarial parasite, Brugia malayi, can be maintained in rodents in the laboratory setting. It has been a widely used model organism in experiments that employ culture systems, the impact of which on the worms is unknown.
c. 2016 Ballesteros et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Ballesteros, Cristina; Tritten, Lucienne; O'Neill, Maeghan; Burkman, Erica; Zaky, Weam I.; Xia, Jianguo; Moorhead, Andrew; Williams, Steven A.; and Geary, Timothy G., "The Effect of In Vitro Cultivation on the Transcriptome of Adult Brugia malayi" (2016). Biological Sciences: Faculty Publications. 6.