Relativistic Effects in Homogeneous Gold Catalysis

Authors

David J. Gorin, University of California, BerkeleyFollow
F. Dean Toste, University of California, Berkeley

Document Type

Article

Publication Date

3-22-2007

Publication Title

Nature

Abstract

Transition-metal catalysts containing gold present new opportunities for chemical synthesis, and it is therefore not surprising that these complexes are beginning to capture the attention of the chemical community. Cationic phosphine-gold(i) complexes are especially versatile and selective catalysts for a growing number of synthetic transformations. The reactivity of these species can be understood in the context of theoretical studies on gold; relativistic effects are especially helpful in rationalizing the reaction manifolds available to gold catalysts. This Review draws on experimental and computational data to present our current understanding of homogeneous gold catalysis, focusing on previously unexplored reactivity and its application to the development of new methodology.

Volume

446

Issue

7134

First Page

395

Last Page

403

DOI

10.1038/nature05592

ISSN

00280836

Rights

©2007 Nature Publishing Group

Comments

Archived as published. Open access article.

Recommended Citation

Gorin, David J. and Toste, F. Dean, "Relativistic Effects in Homogeneous Gold Catalysis" (2007). Chemistry: Faculty Publications, Smith College, Northampton, MA.
https://scholarworks.smith.edu/chm_facpubs/67