Document Type

Article

Publication Date

6-1-2025

Publication Title

Developmental Cognitive Neuroscience

Abstract

Socioeconomic status (SES) is associated with widespread differences in structure of temporal, parietal, occipital, and frontal cortices. Development of sensory processing regions—in particular visual association cortex (VAC) and auditory association cortex (AAC)—may scaffold development of the prefrontal cortex (PFC). Experiences that correlate with SES like cognitive stimulation and language may influence VAC and AAC development, in turn allowing the PFC to resolve conflicts between similar stimuli. SES-related differences in these regions may partly explain differences in executive function (EF) skills. Here, we use structural equation modeling of longitudinal data from the Adolescent Brain and Cognitive Development study to test the hypothesis that SES-related differences in AAC and VAC are associated with differences in structure of the PFC and development of the PFC over time, which in turn are associated with development of EF. We found partial support for this model, demonstrating that SES-related differences in PFC structure are mediated by differences in sensory cortex structure, and that SES-related differences in sensory cortex structure mediate the association between SES and EF. These findings highlight the role sensory processing regions play in SES-related differences in PFC development. Future studies should explore proximal environmental factors driving SES-related differences to inform interventions.

Keywords

Cortical surface area, Cortical thickness, Executive function, Prefrontal cortex, Sensory association cortex, Socioeconomic status

Volume

73

DOI

10.1016/j.dcn.2025.101550

ISSN

18789293

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Rights

Licensed to Smith College and distributed CC-BY 4.0 under the Smith College Faculty Open Access Policy.

Comments

Peer reviewed accepted manuscript.

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