Corrigendum to “Rhythms in barriers and fluids: Circadian clock regulation in the aging neurovascular unit” [Neurobiology of Disease, Volume 181 (1st June 2023) Article Number 106120] (Neurobiology of Disease (2023) 181, (S0969996123001341), (10.1016/j.nbd.2023.106120))

Lea Skapetze, Ludwig-Maximilians-Universität München
Sharon Owino, Smith College
Eng H. Lo, Harvard Medical School
Ken Arai, Harvard Medical School
Martha Merrow, Ludwig-Maximilians-Universität München
Mary Harrington, Smith College

Archived as published.


The authors regret multiple errors in a paragraph. The corrected text should read: “Sleep deprivation has been shown to increase BBB permeability in animal models. For instance, a study conducted in mice demonstrated that sleep deprivation increases BBB permeability to sodium-fluorescein (He et al., 2014). The researchers found that after six days of sleep restriction, the levels of sodium-fluorescein in the brain increased significantly, indicating increased BBB permeability. Another study conducted in rats found that chronic sleep restriction leads to BBB breakdown, resulting in increased infiltration of 70kDa FITC-dextran and Evans Blue into the brain and neuroinflammation (Hurtado-Alvarado et al., 2016).” The correct citation is: Hurtado-Alvarado G, Domínguez-Salazar E, Velázquez-Moctezuma J, Gómez-González B. A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction. PLoS One. 2016 Nov 28;11(11):e0167236. doi: PMID: 27893847; PMCID: PMC5125701. The authors would like to apologise for any inconvenience caused.