Document Type
Conference Proceeding
Publication Date
1-1-1999
Publication Title
Parasitology
Abstract
The initiation of genome projects on helminths of medical importance promises to yield new drug targets and vaccine candidates in unprecedented numbers. In order to exploit this emerging data it is essential that the user community is aware of the scope and quality of data available, and that the genome projects provide analyses of the raw data to highlight potential genes of interest. Core bioinformatics support for the parasite genome projects has promoted these approaches. In the Brugia genome project, a combination of expressed sequence tag sequencing from multiple cDNA libraries representing the complete filarial nematode lifecycle, and comparative analysis of the sequence dataset, particularly using the complete genome sequence of the model nematode C. elegans, has proved very effective in gene discovery.
Keywords
Bioinformatics, Brugia malayi, Caenorhabditis elegans, Expressed sequence tag, Genome mapping, Genomics, Parasitic genomes, Schistosoma
Volume
118
Issue
SUPPL.
ISSN
00311820
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Recommended Citation
Blaxter, M.; Aslett, M.; Guiliano, D.; Daub, J.; Williams, Steven A.; Jayaraman, Kunthala; Ramzy, Reda; Scott, Alan; Supali, Tania; and Slatko, Barton, "Parasitic Helminth Genomics" (1999). Biological Sciences: Faculty Publications, Smith College, Northampton, MA.
https://scholarworks.smith.edu/bio_facpubs/171
Comments
Archived as published. Open access paper.