Document Type

Article

Publication Date

8-1-2018

Publication Title

Cerebral Cortex

Abstract

Long-term memory (LTM) helps to efficiently direct and deploy the scarce resources of the attentional system; however, the neural substrates that support LTM-guidance of visual attention are not well understood. Here, we present results from Fmri experiments that demonstrate that cortical and subcortical regions of a network defined by resting-state functional connectivity are selectively recruited for LTM-guided attention, relative to a similarly demanding stimulus-guided attention paradigm that lacks memory retrieval and relative to a memory retrieval paradigm that lacks covert deployment of attention. Memory-guided visuospatial attention recruited posterior callosal sulcus, posterior precuneus, and lateral intraparietal sulcus bilaterally. Additionally, 3 subcortical regions defined by intrinsic functional connectivity were recruited: the caudate head, mediodorsal thalamus, and cerebellar lobule VI/Crus I. Although the broad resting-state network to which these nodes belong has been referred to as a cognitive control network, the posterior cortical regions activated in the present study are not typically identified with supporting standard cognitive control tasks.We propose that these regions form a Memory-Attention Network that is recruited for processes that integrate mnemonic and stimulus-based representations to guide attention. These findings may have important implications for understanding the mechanisms by which memory retrieval influences attentional deployment.

Keywords

cingulated, functional MRI, lateral IPS, posterior precuneus

Volume

28

Issue

8

First Page

2935

Last Page

2947

DOI

10.1093/cercor/bhx172

ISSN

10473211

Rights

© The Author 2017

Comments

Archived as published.

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