Document Type

Article

Publication Date

10-21-2021

Publication Title

Psychological Medicine

Abstract

Background Neuroticism is associated with the onset and maintenance of a number of mental health conditions, as well as a number of deleterious outcomes (e.g. physical health problems, higher divorce rates, lost productivity, and increased treatment seeking); thus, the consideration of whether this trait can be addressed in treatment is warranted. To date, outcome research has yielded mixed results regarding neuroticism's responsiveness to treatment, perhaps due to the fact that study interventions are typically designed to target disorder symptoms rather than neuroticism itself. The purpose of the current study was to explore whether a course of treatment with the unified protocol (UP), a transdiagnostic intervention that was explicitly developed to target neuroticism, results in greater reductions in neuroticism compared to gold-standard, symptom focused cognitive behavioral therapy (CBT) protocols and a waitlist (WL) control condition. Method Patients with principal anxiety disorders (N = 223) were included in this study. They completed a validated self-report measure of neuroticism, as well as clinician-rated measures of psychological symptoms. Results At week 16, participants in the UP condition exhibited significantly lower levels of neuroticism than participants in the symptom-focused CBT (t(218) =-2.17, p = 0.03, d =-0.32) and WL conditions(t(207) =-2.33, p = 0.02, d =-0.43), and these group differences remained after controlling for simultaneous fluctuations in depression and anxiety symptoms. Conclusions Treatment effects on neuroticism may be most robust when this trait is explicitly targeted.

Keywords

Cognitive-behavioral therapy, neuroticism, transdiagnostic, unified protocol

Volume

51

Issue

14

First Page

2378

Last Page

2387

DOI

10.1017/S0033291720000975

ISSN

00332917

Comments

Peer reviewed accepted manuscript.

Included in

Psychology Commons

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