Document Type
Article
Publication Date
10-14-2020
Publication Title
PLoS Biology
Abstract
Characterization of circadian systems at the organism level—a top-down approach—has led to definition of unifying properties, a hallmark of the science of chronobiology. The next challenge is to use a bottom-up approach to show how the molecular workings of the cellular circadian clock work as building blocks of those properties. We review new studies, including a recently published PLOS Biology paper by Nikhil and colleagues, that show how programmed but also stochastic generation of variation in cellular circadian period explain important adaptive features of entrained circadian phase.
Volume
18
Issue
10
DOI
10.1371/journal.pbio.3000927
ISSN
15449173
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Rights
© 2020 Merrow, Harrington.
Recommended Citation
Merrow, Martha and Harrington, Mary E., "A Functional Context for Heterogeneity of the Circadian Clock in Cells" (2020). Psychology: Faculty Publications, Smith College, Northampton, MA.
https://scholarworks.smith.edu/psy_facpubs/89
Comments
Archived as published.