Document Type

Article

Publication Date

7-1-2010

Publication Title

Journal of Clinical Investigation

Abstract

It is now believed that frequent jet lag or shifts of daily rhythms caused by rotating shift work can lead to deleterious health outcomes. Indeed, many serious health problems, including breast cancer, stroke, and cardiovascular disease, have been linked to an occupational history of shift work. This has heightened interest in better understanding the biological responses to jet lag and shift work, with the hope that this will pave the way to developing compounds that can help people avoid their negative health consequences. In this context, a report in this issue of the JCI takes us to a new level of understanding of the molecular control of the resetting of the multitude of internal biological clocks disrupted in a mouse model of jet lag.

Volume

120

Issue

7

First Page

2265

Last Page

2267

DOI

10.1172/JCI43632

ISSN

00219738

Comments

Archived as published. Open access article.

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