2023
DNA-Palladium Conjugates for Targeted Drug Delivery in Biological Systems, Laura Birkart, Honors Project
Combinatorial Approaches for the Synthesis of Protein-Polymer Conjugates (PPC) for Drug Delivery, Ama Boamah, Honors Project
The Role of Cobalt-Complexed Alkynes in the Diels-Alder Reaction, Ashlyn Bohn, Honors Project
The Structural and Kinetic NMR Studies of the Spiroiminodihydantoin (Sp) Lesion Mismatched to Guanine in a 11-mer DNA Duplex, Jiayun Chen, Honors Project
Effect of Sp Lesions on the Breathing Kinetics of 11-mer DNA Duplexes, Michelle Chen, Honors Project
Progress Toward Identifying Bioactive Sites of Neurolenin Compounds, Nina Glesby, Honors Project
Post-Polymerization Functional Patterning of Polymer Networks for the Development of Chemical Sensors, Anna Lynch, Honors Project
2022
Optimization of Poly(Pentafluorophenyl Acrylate) Polymer-Drug Conjugates for Targeted Drug Delivery, Macy R. Kasbo, Honors Project
Work Toward the Synthesis of Strained Heteroatom-Containing Cyclic Alkynes Using an Intramolecular Nicholas Reaction, Halley M. Lin-Jones, Honors Project
Synthesis of Nitrogen Containing Neurolenin Derivatives as a Potential Drug Against Lymphatic Filariasis, Monalisa Munia, Honors Project
Exploring the Effect of Cobalt-complexed Alkynes on Dienes in Diels-Alder Reactions, Lingyue Grace Ou, Honors Project
Site-Specific Protein-Polymer Conjugation with Activated Ester Polymers for Targeted Cancer Therapy, Jiyun Zhang, Honors Project
2020
Creating finely tuned ultrathin polymeric films on silica via pre-functionalization and post-functionalization methods, Elizabeth Awuor Apiche, Honors Project
Hydrophilic Si(100) with varying typography via post-hydrosilylation functionalization, Yuhui Du, Honors Project
Photomediated post-fabrication modification of azlactone-functionalized gels for the development of stimuli-responsive hydrogel actuators, Emily Ruth Fitzgerald, Honors Project
Chan-Lam O-methylation of aliphatic alcohols and phenolic n-heterocycles, Uma Bhagwat Gaffney, Honors Project
Solvent environments of secondary organic aerosol mimicking solution, Emmaline Reed Longnecker, Honors Project
Synthesis and base pair opening kinetics of the Spiroimminodihydantoin lesion, Ruby C. Wu, Honors Project
Development of a tandem Diels-Alder/Pauson-Khand reaction strategy for the synthesis of a tetracyclic steroid core, Eve Yuanwei Xu, Honors Project
Nucleosomal base excision repair of spiroiminodihydantoin lesions initiated by formamidopyrimidine DNA glycosylase, Linghe Zhang, Honors Project
2019
Mechanism of stereoselective catalysis by Diels-Alderase PyrE3 involved in pyrroindomycins biosynthesis, Xingyi Guan, Honors Project
Hydrogel formation via photocontrolled ring opening reactions of poly(2-alkenyl azlactone)s with photocaged primary amines, Autumn M. Mineo, Honors Project
2018
Chan-Lam aerobic methylation of phenols, Mairead Elizabeth Bartlett, Honors Project
The site specificity of oxidation on water etched Si(100) surface, Xinyuan Chen, Honors Project
Functionalization of neurolenins isolated from Neurolaena lobata, Peyton Higgins, Honors Project
Synthesis and thermodynamic analysis of a cisplatin-modified DNA 12-mey, Sheng Tian, Honors Project
Synthesis of an alkyne-conjugated neurolenin derivative for use in biological click-chemistry experiments, Anisha Tyagi, Honors Project
Univariate and multivariate quantification of hydrogen, lithium, boron, carbon, and sulfur under vacuum and in Earth and Mars atmospheres using laser-induced breakdown spectroscopy, Caroline R. Ytsma, Honors Project
2017
Synthesis and characterization of PEG-PVDMA hydrogels and core-crosslinked mPeg-block-PVDMA micelles for cancer therapy, Quinn Michael Anex-Ries, Honors Project
Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Katherine Anne Blackford, Honors Project
Design and synthesis of a novel cyclic oxazole pseudopeptide, Katherine Anne Graham-O'Regan, Honors Project
The isolation and derivatization of sesquiterpene lactones from Neurolaena lobata, Megan Elizabeth Neubig, Honors Project
Separation of the diastereomers of 2,6-Diisopropylcyclohexanol & synthesis and purification of 2,6-Disubstituted cyclohexanols and cyclohexylamines for application as potential anesthetics, Htoo Tint Wai, Honors Project
Reactive azlactone hydrogels : fundamental characteristics and cell compatability, Megan Marie Wancura, Honors Project
Aerobic, copper catalyzed phenol methylation via the Chan-Lam coupling reaction, Yingchuan Zhu, Honors Project
2016
DNA-catalyst conjugates (DCats) for site-selective chemical transformations in complex milieus, Ana Emilia Arguello, Honors Project
Ethylene carbonate ethoxylation on aromatic nitrogen nucleophiles, Peishan Chen, Honors Project
Copper mediated C-H methylation with methylboronic acid, Clare Elizabeth Jacobson, Honors Project
Investigating varied reactivity in aerosol-mimicking solutions, Claire Elena Keller, Honors Project
Methylation of oxygen nucleophiles using dimethyl carbonate : mechanistic studies, Noelia Margarita Martinez-Muñoz, Honors Project
Extraction and functionalization of Neurolinens from Neuoleana lobata, Catherine Patricia McGeogh, Honors Project
The synthesis and use of stimuli-responsive cross-linkers to prepare PVDMA hydrogels, Isabella Frances McNamara, Honors Project
2015
1D and 2D ¹H NMR spectroscopy studies of mutagenic DNA duplexes, Sophia C. Carroll, Honors Project
DNA-small molecule catalyst conjugates for site-selective chemistry in complex contexts, Drew Elizabeth Colman, Honors Project
A provenance study of ancient Corinthian pottery by non-destructive chemical analysis, Rebecca Frances Gerdes, Honors Project
Simultaneously controlling nanoscale morphology and chemical functionality in the Si(100) surface, Minhee Kim, Honors Project
Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Zulema Maria Peralta, Honors Project
Design of an online learning environment for chemical concepts in bioengineering, Greta Wanless Stacy, Honors Project
2014
Simultaneous control of nanoscale topography and chemical functionalization on the Si(100)surface, Madeleine Sara Beasley, Honors Project
Synthesis of cyclo-[(L-Phe-D-[superscript me]N-Ala)₄-] dimer : a potential ion transporter, Virginia Marcela Diaz, Honors Project
Synthesis and chromatographic separation of the diastereomers of 2,6-Diethylcyclohexanol for application as a potential anesthetic, Alexandra Marie Gatsios, Honors Project
Impact of climate change and invasive species on the chemistry of organic horizons in forested soils from western Massachusetts, Clarke Alexandra Knight, Honors Project
Synthesis of strained cyclic alkynes using an intramolecular cobalt-mediated Nicholas reaction, Gloria Ortiz, Honors Project
The synthesis and chromatographic separation of 2-ethyl-6-methylcyclohexanol, a possible anesthetic, Céleste Marie Pritchard, Honors Project
Mechanistic studies in the base catalyzed methylation of carboxylic acids and phenols, Jessica Susan Sweeney, Honors Project
Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Natalie Vaninov, Honors Project
Catalytic methylation of oxygen nucleophiles by "C₃" and an oxidant, Jillian Zoglio, Honors Project
2013
2D-NMR spectroscopy of mutagenic DNA duplexes, Danielle Anne Chichester, Honors Project
The chelate effect : is it all entropy?, Lisa Stephanie Cunden, Honors Project
Development of a tandem Diels-Alder/Pauson-Khand reaction strategy for the synthesis of tetracycles, Elsa Hinds, Honors Project
Five-coordinate intermediates : why carbon will not behave, Sarah Frances Kay, Honors Project
DNA catalyst conjugates (DCats) for site-selective chemical transformations in complex environments, Jiyeon Kim, Honors Project
Geochemical evidence for the origin of mineralogical rinds surrounding garnet-amphibolite blocks in a subduction zone mélange, Catalina Island, California, Lauren Jeanne Magliozzi, Honors Project
Synthesis and purification of 2,6-dimethylcyclohexanol for application as a general anesthetic, Kelly Aiken Smith, Honors Project
Investigation of the thermodynamic stability of the diastereomeric spiroiminodihydantoin lesion, Elizabeth A. Stewart, Honors Project
2012
Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Catriona Emily Blunt, Honors Project
Dissolved organic carbon in Avery Brook, West Whately, Massachusetts, Susanna M. Michael, Honors Project
The chromatographic separation of the diastereomers of 2,6-Dimethylcyclohexanol, a potential general anesthetic, Alexandra Elizabeth Page, Honors Project
The synthesis and reactivity of a novel cationic Diels-Alder dienophile stabilized by a cobalt-complexed alkyne, Sarah Adler Rothstein, Honors Project
Ruthenium gallops the nicotinamide ring, Eliza Kate Spear, Honors Project
Mn(CO)₅R : why are the carbonyls leaning?, Amelia Catherine Valladares, Honors Project
Accuracy of DNA pairing by the RecA protein : proof of concept for a RecA gene chip, Julea Michelle Vlassakis, Honors Project
An environmentally friendly synthetic approach : making vanillin from colored clay, Lexiaochuan Wen, Honors Project
2011
Controlling surface chemistry on nanopatterned silicon substrates : direct organic functionalization of rough surfaces, Amelia Kate Evans, Honors Project
Investigating the biodiversity of amoebae from the Smith College Plant House, Anastasia Lauren Gant, Honors Project
Structural studies of DNA duplexes using 2-dimensional NMR spectroscopy, Joo Hyun Park, Honors Project
Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Sarah Jacqueline Perlmutter, Honors Project
Probing the molecular architecture of bio-films : an in situ FTIR investigation of Poly-L-lysine and alginate on silicon-based surfaces, Cristina Caridad Santarossa, Honors Project
Clay-catalyzed natural products synthesis : an investigation of a green organic synthesis of vanillin using montmorillonite clay, Anna Margaret Valentine, Honors Project
2010
The Diels-Alder reaction : synthesis of a cationic dienophile, Stephanie Vivian Aldrin, Honors Project
Cationic Diels-Alder dienophiles stablized by cobalt-complexed alkynes, Rachel Ruth Dorset, Honors Project
Disarming bacteria through inhibition of quorum sensing, Leslie Ruth Herndon, Honors Project
Development of a tandem Diels-Alder/Pauson-Khand strategy for synthesis of tetracycles, Julie Ann Olson, Honors Project
Computational study of the C-CI bond length, Anna Reznickova, Honors Project
2008
Understanding biofilm formation : poly-L-lysine mediated adsorption of alginate to functionalized silica surfaces, Jennie Brown, Honors Project
Synthesis of a novel Diels-Alder diene, Seiko Fujii, Honors Project
Mechanistic studies of Palladium enolate complexes, Katherine Kornecki, Honors Project
Expanding the scope of the Dakin-West reaction, Julie Pyle, Honors Project
Cobalt-complexed alkynes in the Diels-Alder reaction, Maureen Reilly, Honors Project
1958
The Schmidt reaction with unsymmetrically substituted 1, 1-diarylethylenes, Marianne Tsuk, Masters Thesis