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2023

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DNA-Palladium Conjugates for Targeted Drug Delivery in Biological Systems, Laura Birkart, Honors Project

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Combinatorial Approaches for the Synthesis of Protein-Polymer Conjugates (PPC) for Drug Delivery, Ama Boamah, Honors Project

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The Role of Cobalt-Complexed Alkynes in the Diels-Alder Reaction, Ashlyn Bohn, Honors Project

2022

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Optimization of Poly(Pentafluorophenyl Acrylate) Polymer-Drug Conjugates for Targeted Drug Delivery, Macy R. Kasbo, Honors Project

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Work Toward the Synthesis of Strained Heteroatom-Containing Cyclic Alkynes Using an Intramolecular Nicholas Reaction, Halley M. Lin-Jones, Honors Project

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Synthesis of Nitrogen Containing Neurolenin Derivatives as a Potential Drug Against Lymphatic Filariasis, Monalisa Munia, Honors Project

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Exploring the Effect of Cobalt-complexed Alkynes on Dienes in Diels-Alder Reactions, Lingyue Grace Ou, Honors Project

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Site-Specific Protein-Polymer Conjugation with Activated Ester Polymers for Targeted Cancer Therapy, Jiyun Zhang, Honors Project

2020

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Creating finely tuned ultrathin polymeric films on silica via pre-functionalization and post-functionalization methods, Elizabeth Awuor Apiche, Honors Project

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Hydrophilic Si(100) with varying typography via post-hydrosilylation functionalization, Yuhui Du, Honors Project

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Photomediated post-fabrication modification of azlactone-functionalized gels for the development of stimuli-responsive hydrogel actuators, Emily Ruth Fitzgerald, Honors Project

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Chan-Lam O-methylation of aliphatic alcohols and phenolic n-heterocycles, Uma Bhagwat Gaffney, Honors Project

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Solvent environments of secondary organic aerosol mimicking solution, Emmaline Reed Longnecker, Honors Project

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Synthesis and base pair opening kinetics of the Spiroimminodihydantoin lesion, Ruby C. Wu, Honors Project

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Development of a tandem Diels-Alder/Pauson-Khand reaction strategy for the synthesis of a tetracyclic steroid core, Eve Yuanwei Xu, Honors Project

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Nucleosomal base excision repair of spiroiminodihydantoin lesions initiated by formamidopyrimidine DNA glycosylase, Linghe Zhang, Honors Project

2019

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Mechanism of stereoselective catalysis by Diels-Alderase PyrE3 involved in pyrroindomycins biosynthesis, Xingyi Guan, Honors Project

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Hydrogel formation via photocontrolled ring opening reactions of poly(2-alkenyl azlactone)s with photocaged primary amines, Autumn M. Mineo, Honors Project

2018

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Chan-Lam aerobic methylation of phenols, Mairead Elizabeth Bartlett, Honors Project

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The site specificity of oxidation on water etched Si(100) surface, Xinyuan Chen, Honors Project

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Functionalization of neurolenins isolated from Neurolaena lobata, Peyton Higgins, Honors Project

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Synthesis and thermodynamic analysis of a cisplatin-modified DNA 12-mey, Sheng Tian, Honors Project

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Synthesis of an alkyne-conjugated neurolenin derivative for use in biological click-chemistry experiments, Anisha Tyagi, Honors Project

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Univariate and multivariate quantification of hydrogen, lithium, boron, carbon, and sulfur under vacuum and in Earth and Mars atmospheres using laser-induced breakdown spectroscopy, Caroline R. Ytsma, Honors Project

2017

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Synthesis and characterization of PEG-PVDMA hydrogels and core-crosslinked mPeg-block-PVDMA micelles for cancer therapy, Quinn Michael Anex-Ries, Honors Project

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Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Katherine Anne Blackford, Honors Project

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Design and synthesis of a novel cyclic oxazole pseudopeptide, Katherine Anne Graham-O'Regan, Honors Project

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The isolation and derivatization of sesquiterpene lactones from Neurolaena lobata, Megan Elizabeth Neubig, Honors Project

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Separation of the diastereomers of 2,6-Diisopropylcyclohexanol & synthesis and purification of 2,6-Disubstituted cyclohexanols and cyclohexylamines for application as potential anesthetics, Htoo Tint Wai, Honors Project

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Reactive azlactone hydrogels : fundamental characteristics and cell compatability, Megan Marie Wancura, Honors Project

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Aerobic, copper catalyzed phenol methylation via the Chan-Lam coupling reaction, Yingchuan Zhu, Honors Project

2016

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DNA-catalyst conjugates (DCats) for site-selective chemical transformations in complex milieus, Ana Emilia Arguello, Honors Project

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Ethylene carbonate ethoxylation on aromatic nitrogen nucleophiles, Peishan Chen, Honors Project

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Copper mediated C-H methylation with methylboronic acid, Clare Elizabeth Jacobson, Honors Project

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Investigating varied reactivity in aerosol-mimicking solutions, Claire Elena Keller, Honors Project

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Methylation of oxygen nucleophiles using dimethyl carbonate : mechanistic studies, Noelia Margarita Martinez-Muñoz, Honors Project

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Extraction and functionalization of Neurolinens from Neuoleana lobata, Catherine Patricia McGeogh, Honors Project

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The synthesis and use of stimuli-responsive cross-linkers to prepare PVDMA hydrogels, Isabella Frances McNamara, Honors Project

2015

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1D and 2D ¹H NMR spectroscopy studies of mutagenic DNA duplexes, Sophia C. Carroll, Honors Project

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DNA-small molecule catalyst conjugates for site-selective chemistry in complex contexts, Drew Elizabeth Colman, Honors Project

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A provenance study of ancient Corinthian pottery by non-destructive chemical analysis, Rebecca Frances Gerdes, Honors Project

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Simultaneously controlling nanoscale morphology and chemical functionality in the Si(100) surface, Minhee Kim, Honors Project

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Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Zulema Maria Peralta, Honors Project

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Design of an online learning environment for chemical concepts in bioengineering, Greta Wanless Stacy, Honors Project

2014

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Simultaneous control of nanoscale topography and chemical functionalization on the Si(100)surface, Madeleine Sara Beasley, Honors Project

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Synthesis of cyclo-[(L-Phe-D-[superscript me]N-Ala)₄-] dimer : a potential ion transporter, Virginia Marcela Diaz, Honors Project

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Synthesis and chromatographic separation of the diastereomers of 2,6-Diethylcyclohexanol for application as a potential anesthetic, Alexandra Marie Gatsios, Honors Project

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Impact of climate change and invasive species on the chemistry of organic horizons in forested soils from western Massachusetts, Clarke Alexandra Knight, Honors Project

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Synthesis of strained cyclic alkynes using an intramolecular cobalt-mediated Nicholas reaction, Gloria Ortiz, Honors Project

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The synthesis and chromatographic separation of 2-ethyl-6-methylcyclohexanol, a possible anesthetic, Céleste Marie Pritchard, Honors Project

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Mechanistic studies in the base catalyzed methylation of carboxylic acids and phenols, Jessica Susan Sweeney, Honors Project

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Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Natalie Vaninov, Honors Project

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Catalytic methylation of oxygen nucleophiles by "C₃" and an oxidant, Jillian Zoglio, Honors Project

2013

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2D-NMR spectroscopy of mutagenic DNA duplexes, Danielle Anne Chichester, Honors Project

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The chelate effect : is it all entropy?, Lisa Stephanie Cunden, Honors Project

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Development of a tandem Diels-Alder/Pauson-Khand reaction strategy for the synthesis of tetracycles, Elsa Hinds, Honors Project

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Five-coordinate intermediates : why carbon will not behave, Sarah Frances Kay, Honors Project

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DNA catalyst conjugates (DCats) for site-selective chemical transformations in complex environments, Jiyeon Kim, Honors Project

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Geochemical evidence for the origin of mineralogical rinds surrounding garnet-amphibolite blocks in a subduction zone mélange, Catalina Island, California, Lauren Jeanne Magliozzi, Honors Project

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Synthesis and purification of 2,6-dimethylcyclohexanol for application as a general anesthetic, Kelly Aiken Smith, Honors Project

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Investigation of the thermodynamic stability of the diastereomeric spiroiminodihydantoin lesion, Elizabeth A. Stewart, Honors Project

2012

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Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Catriona Emily Blunt, Honors Project

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Dissolved organic carbon in Avery Brook, West Whately, Massachusetts, Susanna M. Michael, Honors Project

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The chromatographic separation of the diastereomers of 2,6-Dimethylcyclohexanol, a potential general anesthetic, Alexandra Elizabeth Page, Honors Project

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The synthesis and reactivity of a novel cationic Diels-Alder dienophile stabilized by a cobalt-complexed alkyne, Sarah Adler Rothstein, Honors Project

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Ruthenium gallops the nicotinamide ring, Eliza Kate Spear, Honors Project

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Mn(CO)₅R : why are the carbonyls leaning?, Amelia Catherine Valladares, Honors Project

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Accuracy of DNA pairing by the RecA protein : proof of concept for a RecA gene chip, Julea Michelle Vlassakis, Honors Project

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An environmentally friendly synthetic approach : making vanillin from colored clay, Lexiaochuan Wen, Honors Project

2011

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Controlling surface chemistry on nanopatterned silicon substrates : direct organic functionalization of rough surfaces, Amelia Kate Evans, Honors Project

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Investigating the biodiversity of amoebae from the Smith College Plant House, Anastasia Lauren Gant, Honors Project

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Structural studies of DNA duplexes using 2-dimensional NMR spectroscopy, Joo Hyun Park, Honors Project

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Development of a tandem Diels-Alder/Pauson-Khand strategy for the synthesis of tetracycles, Sarah Jacqueline Perlmutter, Honors Project

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Probing the molecular architecture of bio-films : an in situ FTIR investigation of Poly-L-lysine and alginate on silicon-based surfaces, Cristina Caridad Santarossa, Honors Project

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Clay-catalyzed natural products synthesis : an investigation of a green organic synthesis of vanillin using montmorillonite clay, Anna Margaret Valentine, Honors Project

2010

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The Diels-Alder reaction : synthesis of a cationic dienophile, Stephanie Vivian Aldrin, Honors Project

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Cationic Diels-Alder dienophiles stablized by cobalt-complexed alkynes, Rachel Ruth Dorset, Honors Project

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Disarming bacteria through inhibition of quorum sensing, Leslie Ruth Herndon, Honors Project

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Development of a tandem Diels-Alder/Pauson-Khand strategy for synthesis of tetracycles, Julie Ann Olson, Honors Project

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Computational study of the C-CI bond length, Anna Reznickova, Honors Project

2008

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Understanding biofilm formation : poly-L-lysine mediated adsorption of alginate to functionalized silica surfaces, Jennie Brown, Honors Project

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Synthesis of a novel Diels-Alder diene, Seiko Fujii, Honors Project

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Mechanistic studies of Palladium enolate complexes, Katherine Kornecki, Honors Project

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Expanding the scope of the Dakin-West reaction, Julie Pyle, Honors Project

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Cobalt-complexed alkynes in the Diels-Alder reaction, Maureen Reilly, Honors Project

1958

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The Schmidt reaction with unsymmetrically substituted 1, 1-diarylethylenes, Marianne Tsuk, Masters Thesis