Document Type
Article
Publication Date
5-2019
Publication Title
Menopause
Abstract
Objective: The purpose of this study was to evaluate the relation between FSH and lipid levels in postmenopausal women from the Kuopio Ischaemic Heart Disease Risk Factor Study.
Methods: Postmenopausal women (n = 588) aged 53 to 73 years and not using hormone therapy were included. The relation between FSH and total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TGs) was evaluated using linear regression, adjusting for estradiol, body mass, smoking, and other hormonal and lifestyle factors. The relation between FSH, dyslipidemia, and abnormal lipid levels were also evaluated.
Results: FSH was positively and linearly associated with TC (P = 0.001) and LDL-C (P = 0.01) in all participants, with stronger relations seen in younger compared with older postmenopausal women. FSH was less strongly associated with HDL-C and TG. FSH was not associated with dyslipidemia; however, higher FSH was associated with increased risk of high TC (P = 0.02) and high LDL-C (P = 0.03).
Conclusions: These data suggest that higher FSH in postmenopausal women is related to higher levels of both TC and LDL-C.
Volume
26
Issue
5
First Page
540
Last Page
545
DOI
10.1097/GME.0000000000001273
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Rights
© the authors
Recommended Citation
Serviente, Corinna; Tuomainen, Tomi-Pekka; Virtanen, Jyrki; Witkowski, Sarah; Niskanen, Leo; and Bertone-Johnson, Elizabeth, "Follicle-Stimulating Hormone is Associated with Lipids in Postmenopausal Women" (2019). Exercise and Sport Studies: Faculty Publications, Smith College, Northampton, MA.
https://scholarworks.smith.edu/ess_facpubs/9
Comments
Peer reviewed accepted manuscript.