The Barresi lab investigates the molecular and cellular mechanisms governing how the nervous system is built. Our research is divided into three separate projects to address how neurons are created, how the nervous system gets wired, and what sorts of environmental factors impact neural development. The Barresi Lab uses the Zebrafish (Danio rerio) as a model system to address aspects of neural and glial cell development. We take a multifaceted approach utilizing molecular and genetic techniques combined with classical embryology and high resolution live embryo microscopy to reveal the role of specific genes in mediating precise cellular behaviors during brain development.