2023
Iron-Catalyzed Oxidative α-Amination of Ketones with Primary and Secondary Sulfonamides, Fubin Song, So Hyun Park, Christine Wu, and Alexandra E. Strom
2022
Isolation and Genome Analysis of an Amoeba-Associated Bacterium Dyella terrae Strain Ely Copper Mine From Acid Rock Drainage in Vermont, United States, Lesley Ann Giddings, Kevin Kunstman, Bouziane Moumen, Laurent Asiama, Stefan Green, Vincent Delafont, Matthew Brockley, and Ascel Samba-Louaka
Extremophilic Fungi from Marine Environments: Underexplored Sources of Antitumor, Anti-Infective and Other Biologically Active Agents, Lesley Ann Giddings and David J. Newman
Taking Action: Managing Inclusive Excellence in Academia, Lesley Ann Giddings and Christine Salomon
2021
Cu-Catalyzed Phenol O-Methylation with Methylboronic Acid, Mairead E. Bartlett, Yingchuan Zhu, Uma Bhagwat Gaffney, Joyce Lee, Miranda Wu, Betemariam Sharew, Angela K. Chavez, and David J. Gorin
Characterization of a Broadly Specific Cadaverine N-hydroxylase Involved in Desferrioxamine B Biosynthesis in Streptomyces sviceus, Lesley Ann Giddings, George T. Lountos, Kang Woo Kim, Matthew Brockley, Danielle Needle, Scott Cherry, Joseph E. Tropea, and David S. Waugh
Virtual Buffer Lab, Mohini Kulp
Probing Liquid−Liquid Phase Separation in Secondary Organic Aerosol Mimicking Solutions Using Articulated Straws, Emmaline R. Longnecker, Lucy Metz, Rebecca S. Miller, and Andrew E. Berke
Stratification, Solvent-Modulation in Secondary Organic Aerosol Mimicking Solutions, Emmaline R. Longnecker, Rebecca Miller, Lucy Metz, Asli Ali, Laura Bickart, Michell Chen, Maya Morales, Habso Omane, and Andrew E. Berke
Molecular Design of Polymer Coatings Capable of Photo-Triggered Stress Relaxation via Dynamic Covalent Bond Exchange, Autumn M. Mineo, Maren E. Buck, and Reika Katsumata
Neglected Nematodes: The Neurolenin Solution, Kevin M. Shea and Steven Williams
2020
Semester-Long Course-Based Research Project in Second-Semester Organic Chemistry: Synthesizing Potential Lead Compounds for the Treatment of a Neglected Tropical Disease, Kerry L. Barnett, Kevin M. Shea, Catherine McGeough, Kristine Trotta, Steven A. Williams, Minh Ly, and Kathryn Aloisio
ASP Diversity and Inclusion Committee Call to Action, Nadja Cech, Christine Salomon, Susan Mooberry, Sandra Loesgen, Katharine Watts, Josh Kellogg, Lesley Ann Giddings, Brian T. Murphy, and Esther A. Guzmán
Taking Action: Intentional Inclusivity, Lesley Ann Giddings
Seasonal Ely Copper Mine Superfund Site Shotgun Metagenomic and Metatranscriptomic Data Analysis, Lesley Ann Giddings, George Chlipala, Heather Driscoll, Kieran Bhave, Kevin Kunstman, Stefan Green, Katherine Morillo, Holly Peterson, and Mark Maienschein-Cline
Characterization of an Acid Rock Drainage Microbiome and Transcriptome at the Ely Copper Mine Superfund Site, Lesley Ann Giddings, George Chlipala, Kevin Kunstman, Stefan Green, Katherine Morillo, Kieran Bhave, Holly Peterson, Heather Driscoll, and Mark Maienschein-Cline
First-Semester Organic Chemistry During COVID-19: Prioritizing Group Work, Flexibility, and Student Engagement, Leslie A. Nickerson and Kevin M. Shea
2019
Protein-Polymer Conjugates Synthesized Using Water-Soluble Azlactone-Functionalized Polymers Enable Receptor-Specific Cellular Uptake Toward Targeted Drug Delivery, Julia S. Kim, Allison R. Sirois, Analia J. Vazquez Cegla, Eugenie Jumai'an, Naomi Murata, Maren E. Buck, and Sarah J. Moore
Ni-Catalyzed Cross-Electrophile Coupling for the Synthesis of Skipped Polyenes, Catherine P. McGeough, Alexandra E. Strom, and Timothy F. Jamison
2018
A DNA-Conjugated Small Molecule Catalyst Enzyme Mimic for Site-Selective Ester Hydrolysis, Moira L. Flanagan, A. Emilia Arguello, Drew E. Colman, Jiyeon Kim, Jesse N. Krejci, Shimu Liu, Yueyu Yao, Yu Zhang, and David J. Gorin
Mechanistic Studies of Palladium-Catalyzed Aminocarbonylation of Aryl Chlorides with Carbon Monoxide and Ammonia, Justin Y. Wang, Alexandra E. Strom, and John F. Hartwig
Deconvoluting the Effects of Surface Chemistry and Nanoscale Topography: Pseudomonas aeruginosa Biofilm Nucleation on Si-based Substrates, Zhang Zhang, Jingling Huang, Carmen Say, Robert L. Dorit, and Kate Queeney
2017
Analysis and Control of Chain Mobility in Protein Hydrogels, Peter B. Rapp, Ahmad K. Omar, Jeff J. Shen, Maren E. Buck, Zhen Gang Wang, and David A. Tirrell
2016
Differential Potency of 2,6-Dimethylcyclohexanol Isomers for Positive Modulation of GABAA Receptor Currents, Luvana Chowdhury, Celine J. Croft, Shikha Goel, Naina Zaman, Angela C.-S. Tai, Erin M. Walch, Alexandra Page, Kevin M. Shea, C. Dennis Hall, D. Jishkariani, Girinath G. Pillai, and Adam C. Hall
Programming Molecular Association and Viscoelastic Behavior in Protein Networks, Lawrence J. Dooling, Maren E. Buck, Wen Bin Zhang, and David A. Tirrell
The “pHunger Games”: Manuscript Review to Assess Graduating Chemistry Majors, David J. Gorin, Elizabeth R. Jamieson, Kate Queeny, Kevin M. Shea, and Carrie G. Read Spray
Effect of Base-Pairing Partner on the Thermodynamic Stability of the Diastereomeric Spiroiminodihydantoin Lesion, Brian Gruessner, Megana Dwarakanath, Elizabeth Stewart, Yoon Bae, and Elizabeth R. Jamieson
Effect of the Spiroiminodihydantoin Lesion on Nucleosome Stability and Positioning, Erika Norabuena, Sara Barnes Williams, Margaret A. Klureza, Liana J. Goehring, Brian Gruessner, Mala L. Radhakrishnan, Elizabeth R. Jamieson, and Megan E. Núñez
Beyond Clickers, Next Generation Classroom Response Systems for Organic Chemistry, Kevin M. Shea
Literature-Based Problems for Introductory Organic Chemistry Quizzes and Exams, Kevin M. Shea, David J. Gorin, and Maren E. Buck
Synthetic and Computational Studies on the Rhodium-Catalyzed Hydroamination of Aminoalkenes, Alexandra E. Strom, David Balcells, and John F. Hartwig
2015
Aerobic Copper-Catalyzed O-Methylation with Methylboronic Acid, Clare E. Jacobson, Noella Martinez-Muñoz, and David J. Gorin
2013
Microbial Natural Products: Molecular Blueprints for Antitumor Drugs, Lesley Ann Giddings and David J. Newman
Catalytic Methyl Transfer from Dimethylcarbonate to Carboxylic Acids, Yuan Ji, Jessica Sweeney, Jillian Zoglio, and David J. Gorin
One-Pot Anti-Markovnikov Hydroamination of Unactivated Alkenes by Hydrozirconation and Amination, Alexandra E. Strom and John F. Hartwig
2012
In situ Synthesis of Oligonucleotide Arrays on Surfaces Coated with Crosslinked Polymer Multilayers, Adam H. Broderick, Matthew R. Lockett, Maren E. Buck, Yuan Yuan, Lloyd M. Smith, and David M. Lynn
Azlactone-Functionalized Polymers as Reactive Platforms for the Design of Advanced Materials: Progress in the Last Ten Years, Maren E. Buck and David M. Lynn
Additions and Corrections. Critical Perspective: Named Reactions Discovered and Developed by Women, Julie A. Olsen and Kevin M. Shea
Synthesis of Di- and Trisubstituted Azulenes Using a Danheiser Annulation as the Key Step: An Advanced Organic Laboratory Experiment, Rebecca M. Thomas and Kevin M. Shea
2011
Fabrication and Selective Functionalization of Amine-Reactive Polymer Multilayers on Topographically Patterned Microwell Cell Culture Arrays, Adam H. Broderick, Samira M. Azarin, Maren E. Buck, Sean P. Palecek, and David M. Lynn
Layer-by-Layer Fabrication of Covalently Crosslinked and Reactive Polymer Multilayers Using Azlactone-Functionalized Copolymers: A Platform for the Design of Functional Biointerfaces, Maren E. Buck and David M. Lynn
A Stereoselective Hydroxylation Step of Alkaloid Biosynthesis by a Unique Cytochrome P450 in Catharanthus roseus, Lesley Ann Giddings, David K. Liscombe, John P. Hamilton, Kevin L. Childs, Dean DellaPenna, C. Robin Buell, and Sarah E. O'Connor
The Evolution of Function in Strictosidine Synthase-Like Proteins, Michael A. Hicks, Alan E. Barber, Lesley Ann Giddings, Jenna Caldwell, Sarah E. O'Connor, and Patricia C. Babbitt
Critical Perspective: Named Reactions Discovered and Developed by Women, Julie A. Olsen and Kevin M. Shea
Fabrication of Covalently Crosslinked and Amine-Reactive Microcapsules by Reactive Layer-by-Layer Assembly of Azlactone-Containing Polymer Multilayers on Sacrificial Microparticle templates, Eric M. Saurer, Ryan M. Flessner, Maren E. Buck, and David M. Lynn
2010
Free-Standing and Reactive Thin Films Fabricated by Covalent Layer-by-Layer Assembly and Subsequent Lift-Off of Azlactone-Containing Polymer Multilayers, Maren E. Buck and David M. Lynn
Functionalization of Fibers Using Azlactone-Containing Polymers: Layer-by-Layer Fabrication of Reactive Thin Films on the Surfaces of Hair and Cellulose-Based Materials, Maren E. Buck and David M. Lynn
Reactive Layer-by-Layer Assembly of Suspended Thin Films and Semipermeable Membranes at Interfaces Created Between Aqueous and Organic Phases, Maren E. Buck and David M. Lynn
Superhydrophobic Thin Films Fabricated by Reactive Layer-by-Layer Assembly of Azlactone-Functionalized Polymers, Maren E. Buck, Sarina C. Schwartz, and David M. Lynn
Nano-Imprinted Thin Films of Reactive, Azlactone-Containing Polymers: Combining Methods for the Topographic Patterning of Cell Substrates with Opportunities for Facile Post-Fabrication Chemical Functionalization, Nathaniel J. Fredin, Ryan M. Flessner, Christopher M. Jewell, Shane L. Bechler, Maren E. Buck, and David M. Lynn
Immobilization of Polymer-Decorated Liquid Crystal Droplets on Chemically Tailored Surfaces, Michael I. Kinsinger, Maren E. Buck, Nicholas L. Abbott, and David M. Lynn
Langmuir Films of Flexible Polymers Transferred to Aqueous/Liquid Crystal Interfaces Induce Uniform Azimuthal Alignment of the Liquid Crystal, Michael I. Kinsinger, Maren E. Buck, Maria Victoria Meli, Nicholas L. Abbott, and David M. Lynn
Interaction-Dependent PCR: Identification of Ligand-Target Pairs from Libraries of Ligands and Libraries of Targets in a Single Solution-Phase Experiment, Lynn M. McGregor, David J. Gorin, Christoph E. Dumelin, and David R. Liu
Azlactone-Functionalized Polymers as Reactive Templates for Parallel Polymer Synthesis: Synthesis and Screening of a Small Library of Cationic Polymers in the Context of DNA Delivery, Bin Sun, Xianghui Liu, Maren E. Buck, and David M. Lynn
2009
Chemical Modification of Reactive Multilayered Films Fabricated from Poly(2-Alkenyl Azlactone)s: Design of Surfaces that Prevent or Promote Mammalian Cell Adhesion and Bacterial Biofilm growth, Maren E. Buck, Anthony S. Breitbach, Sonja K. Belgrade, Helen E. Blackwell, and David M. Lynn
The Scope and Limitations of Intramolecular Nicholas and Pauson-Khand Reactions for the Synthesis of Tricyclic Oxygen- and Nitrogen-Containing Heterocycles, Kristina D. Closser, Miriam M. Quintal, and Kevin M. Shea
Nano-Imprinted Thin Films of Reactive, Azlactone-Containing Polymers: Combining Methods for the Topographic Patterning of Cell Substrates with Opportunities for Facile Post-Fabrication Chemical Functionalization, Nathaniel J. Fredin, Adam H. Broderick, Maren E. Buck, and David M. Lvnn
Reactivity-Dependent PCR: Direct, Solution-Phase In Vitro Selection for Bond Formation, David J. Gorin, Adam S. Kamlet, and David R. Liu
2008
Ligand Effects in Homogeneous Au Catalysis, David J. Gorin, Benjamin D. Sherry, and F. Dean Toste
Fluorenes and Styrenes by Au(I)-Catalyzed Annulation of Enynes and Alkynes, David J. Gorin, Iain D.G. Watson, and F. Dean Toste
Dynamic Ordering Transitions of Liquid Crystals Driven by Interfacial Complexes Formed Between Polyanions and Amphiphilic Polyamines, Michael I. Kinsinger, Maren E. Buck, Fernando Campos, David M. Lynn, and Nicholas L. Abbott
Strictosidine Synthase: Mechanism of a Pictet-Spengler Catalyzing Enzyme, Justin J. Maresh, Lesley Ann Giddings, Anne Friedrich, Elke A. Loris, Santosh Panjikar, Bernhardt L. Trout, Joachim Stöckigt, Baron Peters, and Sarah E. O'Connor
2007
Relativistic Effects in Homogeneous Gold Catalysis, David J. Gorin and F. Dean Toste
2006
Domain Architecture of Protein-disulfide Isomerase Facilitates Its Dual Role as an Oxidase and an Isomerase in Ero1p-Mediated Disulfide Formation, Mohini Kulp, Eva Maria Frickel, Lars Ellgaard, and Jonathan S. Weissman
2005
Nicholas Reactions with Carboxylic Acids for the Synthesis of Macrocyclic Diolides, Kevin M. Shea, Kristina D. Closser, and Miriam M. Quintal
2004
Tandem Intramolecular Nicholas and Pauson-Khand Reactions for the Synthesis of Tricyclic Oxygen-Containing Heterocycles, Miriam M. Quintal, Kristina D. Closser, and Kevin M. Shea
1999
Structural and Kinetic Studies of a Cisplatin-modified DNA Icosamer Binding to HMG1 Domain B*, Elizabeth R. Jamieson, Matthew P. Jacobson, Carmen M. Barnes, Christine S. Chow, and Stephen J. Lippard
1997
Suprachiasmatic Nucleus Neurons Are Glucose Sensitive, Adam C. Hall, Roselle M. Hoffmaster, Edra L. Stern, Mary E. Harrington, and David Bickar
1996
Contrast-Enhanced Magnetic Resonance Imaging Confirmation of an Anterior Protein Pathway in Normal Rabbit Eyes, Nancy H. Kolodny, Thomas F. Freddo, Barbara A. Lawrence, Cristina Suarez, and Stephen P. Bartels
1986
The Mechanism by which Oxygen and Cytochrome c Increase the Rate of Electron Transfer from Cytochrome a to Cytochrome a3 of Cytochrome c Oxidase, D. Bickar, J. F. Turrens, and A. L. Lehninger
1985
Kinetics of Reduction of Cytochrome c Oxidase by Dithionite and the Effect of Hydrogen Peroxide, M. Brunori, D. Bickar, J. Bonaventura, and C. Bonaventura
1984
Carbon Monoxide-Driven Reduction of Ferric Heme and Heme Proteins, D. Bickar, C. Bonaventura, and J. Bonaventura
A Re-Examination of the Reactions of Cyanide with Cytochrome c Oxidase, M. G. Jones, D. Bickar, M. T. Wilson, M. Brunori, A. Colosimo, and P. Sarti
1963
Atomism in Late Nineteenth-Century Physical Chemistry, George Fleck