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2024

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Outlining the Hidden Curriculum: Perspectives on Successfully Navigating Scientific Conferences, Eduardo J. Caro-Diaz, Marcy J. Balunas, Lesley Ann Giddings, Sandra Loesgen, Brian T. Murphy, C. Benjamin Naman, Christine E. Salomon, Kevin J. Tidgewell, and Jaclyn M. Winter

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Mechanism of Iron-Catalyzed Oxidative α-Amination of Ketones with Sulfonamides, Gloria M. Parrales, Nina C. Hollin, Fubin Song, Yangyang Lyu, Anne-Marie O. Martin, and Alexandra E. Strom

2023

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Genomic and Phenotypic Characterization of a Red-Pigmented Strain of Massilia frigida Isolated from an Antarctic Microbial Mat, Jacob M.C. Scaffer, Lesley Ann Giddings, Robert M. Samples, and Jill A. Mikucki

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Iron-Catalyzed Oxidative α-Amination of Ketones with Primary and Secondary Sulfonamides, Fubin Song, So Hyun Park, Christine Wu, and Alexandra E. Strom

2022

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Isolation and Genome Analysis of an Amoeba-Associated Bacterium Dyella terrae Strain Ely Copper Mine From Acid Rock Drainage in Vermont, United States, Lesley Ann Giddings, Kevin Kunstman, Bouziane Moumen, Laurent Asiama, Stefan Green, Vincent Delafont, Matthew Brockley, and Ascel Samba-Louaka

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Extremophilic Fungi from Marine Environments: Underexplored Sources of Antitumor, Anti-Infective and Other Biologically Active Agents, Lesley Ann Giddings and David J. Newman

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Taking Action: Managing Inclusive Excellence in Academia, Lesley Ann Giddings and Christine Salomon

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Taking Action: Two Years after the ASP Diversity, Equity and Inclusion Committee’s Call to Action, Lesley Ann Giddings, Christine Salomon, and ASP DEI Committee

2021

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Cu-Catalyzed Phenol O-Methylation with Methylboronic Acid, Mairead E. Bartlett, Yingchuan Zhu, Uma Bhagwat Gaffney, Joyce Lee, Miranda Wu, Betemariam Sharew, Angela K. Chavez, and David J. Gorin

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Characterization of a Broadly Specific Cadaverine N-hydroxylase Involved in Desferrioxamine B Biosynthesis in Streptomyces sviceus, Lesley Ann Giddings, George T. Lountos, Kang Woo Kim, Matthew Brockley, Danielle Needle, Scott Cherry, Joseph E. Tropea, and David S. Waugh

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Virtual Buffer Lab, Mohini Kulp

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Probing Liquid−Liquid Phase Separation in Secondary Organic Aerosol Mimicking Solutions Using Articulated Straws, Emmaline R. Longnecker, Lucy Metz, Rebecca S. Miller, and Andrew E. Berke

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Stratification, Solvent-Modulation in Secondary Organic Aerosol Mimicking Solutions, Emmaline R. Longnecker, Rebecca Miller, Lucy Metz, Asli Ali, Laura Bickart, Michell Chen, Maya Morales, Habso Omane, and Andrew E. Berke

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Molecular Design of Polymer Coatings Capable of Photo-Triggered Stress Relaxation via Dynamic Covalent Bond Exchange, Autumn M. Mineo, Maren E. Buck, and Reika Katsumata

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Neglected Nematodes: The Neurolenin Solution, Kevin M. Shea and Steven Williams

2020

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Semester-Long Course-Based Research Project in Second-Semester Organic Chemistry: Synthesizing Potential Lead Compounds for the Treatment of a Neglected Tropical Disease, Kerry L. Barnett, Kevin M. Shea, Catherine McGeough, Kristine Trotta, Steven A. Williams, Minh Ly, and Kathryn Aloisio

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ASP Diversity and Inclusion Committee Call to Action, Nadja Cech, Christine Salomon, Susan Mooberry, Sandra Loesgen, Katharine Watts, Josh Kellogg, Lesley Ann Giddings, Brian T. Murphy, and Esther A. Guzmán

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Taking Action: Intentional Inclusivity, Lesley Ann Giddings

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Seasonal Ely Copper Mine Superfund Site Shotgun Metagenomic and Metatranscriptomic Data Analysis, Lesley Ann Giddings, George Chlipala, Heather Driscoll, Kieran Bhave, Kevin Kunstman, Stefan Green, Katherine Morillo, Holly Peterson, and Mark Maienschein-Cline

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Characterization of an Acid Rock Drainage Microbiome and Transcriptome at the Ely Copper Mine Superfund Site, Lesley Ann Giddings, George Chlipala, Kevin Kunstman, Stefan Green, Katherine Morillo, Kieran Bhave, Holly Peterson, Heather Driscoll, and Mark Maienschein-Cline

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First-Semester Organic Chemistry During COVID-19: Prioritizing Group Work, Flexibility, and Student Engagement, Leslie A. Nickerson and Kevin M. Shea

2019

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Protein-Polymer Conjugates Synthesized Using Water-Soluble Azlactone-Functionalized Polymers Enable Receptor-Specific Cellular Uptake Toward Targeted Drug Delivery, Julia S. Kim, Allison R. Sirois, Analia J. Vazquez Cegla, Eugenie Jumai'an, Naomi Murata, Maren E. Buck, and Sarah J. Moore

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Ni-Catalyzed Cross-Electrophile Coupling for the Synthesis of Skipped Polyenes, Catherine P. McGeough, Alexandra E. Strom, and Timothy F. Jamison

2018

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A DNA-Conjugated Small Molecule Catalyst Enzyme Mimic for Site-Selective Ester Hydrolysis, Moira L. Flanagan, A. Emilia Arguello, Drew E. Colman, Jiyeon Kim, Jesse N. Krejci, Shimu Liu, Yueyu Yao, Yu Zhang, and David J. Gorin

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Mechanistic Studies of Palladium-Catalyzed Aminocarbonylation of Aryl Chlorides with Carbon Monoxide and Ammonia, Justin Y. Wang, Alexandra E. Strom, and John F. Hartwig

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Deconvoluting the Effects of Surface Chemistry and Nanoscale Topography: Pseudomonas aeruginosa Biofilm Nucleation on Si-based Substrates, Zhang Zhang, Jingling Huang, Carmen Say, Robert L. Dorit, and Kate Queeney

2017

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Analysis and Control of Chain Mobility in Protein Hydrogels, Peter B. Rapp, Ahmad K. Omar, Jeff J. Shen, Maren E. Buck, Zhen Gang Wang, and David A. Tirrell

2016

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Differential Potency of 2,6-Dimethylcyclohexanol Isomers for Positive Modulation of GABAA Receptor Currents, Luvana Chowdhury, Celine J. Croft, Shikha Goel, Naina Zaman, Angela C.-S. Tai, Erin M. Walch, Alexandra Page, Kevin M. Shea, C. Dennis Hall, D. Jishkariani, Girinath G. Pillai, and Adam C. Hall

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Programming Molecular Association and Viscoelastic Behavior in Protein Networks, Lawrence J. Dooling, Maren E. Buck, Wen Bin Zhang, and David A. Tirrell

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The “pHunger Games”: Manuscript Review to Assess Graduating Chemistry Majors, David J. Gorin, Elizabeth R. Jamieson, Kate Queeny, Kevin M. Shea, and Carrie G. Read Spray

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Effect of Base-Pairing Partner on the Thermodynamic Stability of the Diastereomeric Spiroiminodihydantoin Lesion, Brian Gruessner, Megana Dwarakanath, Elizabeth Stewart, Yoon Bae, and Elizabeth R. Jamieson

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Effect of the Spiroiminodihydantoin Lesion on Nucleosome Stability and Positioning, Erika Norabuena, Sara Barnes Williams, Margaret A. Klureza, Liana J. Goehring, Brian Gruessner, Mala L. Radhakrishnan, Elizabeth R. Jamieson, and Megan E. Núñez

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Beyond Clickers, Next Generation Classroom Response Systems for Organic Chemistry, Kevin M. Shea

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Literature-Based Problems for Introductory Organic Chemistry Quizzes and Exams, Kevin M. Shea, David J. Gorin, and Maren E. Buck

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Synthetic and Computational Studies on the Rhodium-Catalyzed Hydroamination of Aminoalkenes, Alexandra E. Strom, David Balcells, and John F. Hartwig

2015

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Aerobic Copper-Catalyzed O-Methylation with Methylboronic Acid, Clare E. Jacobson, Noella Martinez-Muñoz, and David J. Gorin

2013

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Microbial Natural Products: Molecular Blueprints for Antitumor Drugs, Lesley Ann Giddings and David J. Newman

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Catalytic Methyl Transfer from Dimethylcarbonate to Carboxylic Acids, Yuan Ji, Jessica Sweeney, Jillian Zoglio, and David J. Gorin

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One-Pot Anti-Markovnikov Hydroamination of Unactivated Alkenes by Hydrozirconation and Amination, Alexandra E. Strom and John F. Hartwig

2012

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In situ Synthesis of Oligonucleotide Arrays on Surfaces Coated with Crosslinked Polymer Multilayers, Adam H. Broderick, Matthew R. Lockett, Maren E. Buck, Yuan Yuan, Lloyd M. Smith, and David M. Lynn

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Azlactone-Functionalized Polymers as Reactive Platforms for the Design of Advanced Materials: Progress in the Last Ten Years, Maren E. Buck and David M. Lynn

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Additions and Corrections. Critical Perspective: Named Reactions Discovered and Developed by Women, Julie A. Olsen and Kevin M. Shea

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Synthesis of Di- and Trisubstituted Azulenes Using a Danheiser Annulation as the Key Step: An Advanced Organic Laboratory Experiment, Rebecca M. Thomas and Kevin M. Shea

2011

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Fabrication and Selective Functionalization of Amine-Reactive Polymer Multilayers on Topographically Patterned Microwell Cell Culture Arrays, Adam H. Broderick, Samira M. Azarin, Maren E. Buck, Sean P. Palecek, and David M. Lynn

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Layer-by-Layer Fabrication of Covalently Crosslinked and Reactive Polymer Multilayers Using Azlactone-Functionalized Copolymers: A Platform for the Design of Functional Biointerfaces, Maren E. Buck and David M. Lynn

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A Stereoselective Hydroxylation Step of Alkaloid Biosynthesis by a Unique Cytochrome P450 in Catharanthus roseus, Lesley Ann Giddings, David K. Liscombe, John P. Hamilton, Kevin L. Childs, Dean DellaPenna, C. Robin Buell, and Sarah E. O'Connor

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The Evolution of Function in Strictosidine Synthase-Like Proteins, Michael A. Hicks, Alan E. Barber, Lesley Ann Giddings, Jenna Caldwell, Sarah E. O'Connor, and Patricia C. Babbitt

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Critical Perspective: Named Reactions Discovered and Developed by Women, Julie A. Olsen and Kevin M. Shea

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Fabrication of Covalently Crosslinked and Amine-Reactive Microcapsules by Reactive Layer-by-Layer Assembly of Azlactone-Containing Polymer Multilayers on Sacrificial Microparticle templates, Eric M. Saurer, Ryan M. Flessner, Maren E. Buck, and David M. Lynn

2010

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Free-Standing and Reactive Thin Films Fabricated by Covalent Layer-by-Layer Assembly and Subsequent Lift-Off of Azlactone-Containing Polymer Multilayers, Maren E. Buck and David M. Lynn

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Functionalization of Fibers Using Azlactone-Containing Polymers: Layer-by-Layer Fabrication of Reactive Thin Films on the Surfaces of Hair and Cellulose-Based Materials, Maren E. Buck and David M. Lynn

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Reactive Layer-by-Layer Assembly of Suspended Thin Films and Semipermeable Membranes at Interfaces Created Between Aqueous and Organic Phases, Maren E. Buck and David M. Lynn

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Superhydrophobic Thin Films Fabricated by Reactive Layer-by-Layer Assembly of Azlactone-Functionalized Polymers, Maren E. Buck, Sarina C. Schwartz, and David M. Lynn

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Nano-Imprinted Thin Films of Reactive, Azlactone-Containing Polymers: Combining Methods for the Topographic Patterning of Cell Substrates with Opportunities for Facile Post-Fabrication Chemical Functionalization, Nathaniel J. Fredin, Ryan M. Flessner, Christopher M. Jewell, Shane L. Bechler, Maren E. Buck, and David M. Lynn

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Immobilization of Polymer-Decorated Liquid Crystal Droplets on Chemically Tailored Surfaces, Michael I. Kinsinger, Maren E. Buck, Nicholas L. Abbott, and David M. Lynn

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Langmuir Films of Flexible Polymers Transferred to Aqueous/Liquid Crystal Interfaces Induce Uniform Azimuthal Alignment of the Liquid Crystal, Michael I. Kinsinger, Maren E. Buck, Maria Victoria Meli, Nicholas L. Abbott, and David M. Lynn

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Interaction-Dependent PCR: Identification of Ligand-Target Pairs from Libraries of Ligands and Libraries of Targets in a Single Solution-Phase Experiment, Lynn M. McGregor, David J. Gorin, Christoph E. Dumelin, and David R. Liu

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Azlactone-Functionalized Polymers as Reactive Templates for Parallel Polymer Synthesis: Synthesis and Screening of a Small Library of Cationic Polymers in the Context of DNA Delivery, Bin Sun, Xianghui Liu, Maren E. Buck, and David M. Lynn

2009

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Chemical Modification of Reactive Multilayered Films Fabricated from Poly(2-Alkenyl Azlactone)s: Design of Surfaces that Prevent or Promote Mammalian Cell Adhesion and Bacterial Biofilm growth, Maren E. Buck, Anthony S. Breitbach, Sonja K. Belgrade, Helen E. Blackwell, and David M. Lynn

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The Scope and Limitations of Intramolecular Nicholas and Pauson-Khand Reactions for the Synthesis of Tricyclic Oxygen- and Nitrogen-Containing Heterocycles, Kristina D. Closser, Miriam M. Quintal, and Kevin M. Shea

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Nano-Imprinted Thin Films of Reactive, Azlactone-Containing Polymers: Combining Methods for the Topographic Patterning of Cell Substrates with Opportunities for Facile Post-Fabrication Chemical Functionalization, Nathaniel J. Fredin, Adam H. Broderick, Maren E. Buck, and David M. Lvnn

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Reactivity-Dependent PCR: Direct, Solution-Phase In Vitro Selection for Bond Formation, David J. Gorin, Adam S. Kamlet, and David R. Liu

2008

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Ligand Effects in Homogeneous Au Catalysis, David J. Gorin, Benjamin D. Sherry, and F. Dean Toste

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Fluorenes and Styrenes by Au(I)-Catalyzed Annulation of Enynes and Alkynes, David J. Gorin, Iain D.G. Watson, and F. Dean Toste

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Dynamic Ordering Transitions of Liquid Crystals Driven by Interfacial Complexes Formed Between Polyanions and Amphiphilic Polyamines, Michael I. Kinsinger, Maren E. Buck, Fernando Campos, David M. Lynn, and Nicholas L. Abbott

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Strictosidine Synthase: Mechanism of a Pictet-Spengler Catalyzing Enzyme, Justin J. Maresh, Lesley Ann Giddings, Anne Friedrich, Elke A. Loris, Santosh Panjikar, Bernhardt L. Trout, Joachim Stöckigt, Baron Peters, and Sarah E. O'Connor

2007

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Relativistic Effects in Homogeneous Gold Catalysis, David J. Gorin and F. Dean Toste

2006

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Domain Architecture of Protein-disulfide Isomerase Facilitates Its Dual Role as an Oxidase and an Isomerase in Ero1p-Mediated Disulfide Formation, Mohini Kulp, Eva Maria Frickel, Lars Ellgaard, and Jonathan S. Weissman

2005

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Nicholas Reactions with Carboxylic Acids for the Synthesis of Macrocyclic Diolides, Kevin M. Shea, Kristina D. Closser, and Miriam M. Quintal

2004

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Tandem Intramolecular Nicholas and Pauson-Khand Reactions for the Synthesis of Tricyclic Oxygen-Containing Heterocycles, Miriam M. Quintal, Kristina D. Closser, and Kevin M. Shea

1999

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Structural and Kinetic Studies of a Cisplatin-modified DNA Icosamer Binding to HMG1 Domain B*, Elizabeth R. Jamieson, Matthew P. Jacobson, Carmen M. Barnes, Christine S. Chow, and Stephen J. Lippard

1997

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Suprachiasmatic Nucleus Neurons Are Glucose Sensitive, Adam C. Hall, Roselle M. Hoffmaster, Edra L. Stern, Mary E. Harrington, and David Bickar

1996

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Contrast-Enhanced Magnetic Resonance Imaging Confirmation of an Anterior Protein Pathway in Normal Rabbit Eyes, Nancy H. Kolodny, Thomas F. Freddo, Barbara A. Lawrence, Cristina Suarez, and Stephen P. Bartels

1986

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The Mechanism by which Oxygen and Cytochrome c Increase the Rate of Electron Transfer from Cytochrome a to Cytochrome a3 of Cytochrome c Oxidase, D. Bickar, J. F. Turrens, and A. L. Lehninger

1985

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Kinetics of Reduction of Cytochrome c Oxidase by Dithionite and the Effect of Hydrogen Peroxide, M. Brunori, D. Bickar, J. Bonaventura, and C. Bonaventura

1984

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Carbon Monoxide-Driven Reduction of Ferric Heme and Heme Proteins, D. Bickar, C. Bonaventura, and J. Bonaventura

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A Re-Examination of the Reactions of Cyanide with Cytochrome c Oxidase, M. G. Jones, D. Bickar, M. T. Wilson, M. Brunori, A. Colosimo, and P. Sarti

1963

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Atomism in Late Nineteenth-Century Physical Chemistry, George Fleck